Polynucleotides PLinest HPT®

Advanced Skin Regeneration from Within

Polynucleotides HPT® (PN-HPT®) are highly purified DNA molecules extracted from trout, specifically designed to stimulate skin regeneration at a cellular level. When injected into the skin, these molecules reach fibroblast cells, which are responsible for producing collagen. This process helps restore skin firmness, elasticity, and hydration, effectively reducing signs of aging.

PN-HPT® also possesses powerful anti-inflammatory and antioxidant properties, helping to calm redness, repair damaged tissue, and protect against environmental stressors. These treatments are ideal for individuals looking to smooth wrinkles, improve skin texture, and restore a youthful glow.

What areas can be treated?

  • Face (cheeks, nasolabial folds, smile lines)
  • Neck & Décolletage
  • Perioral area (fine lines above the lips)
  • Eye area (dark circles, crepiness, fine lines)
Plinest – 3 sessions – micro boluses technique

How it works

PN-HPT® is delivered using precise micro-injections into targeted areas of the face, neck, or décolletage. Once introduced, the polynucleotides work to:

  • Stimulate fibroblasts – encouraging the production of collagen and elastin
  • Enhance hydration – improving skin texture, plumpness, and elasticity
  • Support cell turnover – revitalising tired, damaged, or ageing skin
  • Neutralise free radicals – with powerful antioxidant action
  • Repair tissue – making it ideal for sensitive or compromised skin

benefits include:

  • Firmer, more elastic skin through increased collagen production
  • Improved hydration and reduced crepiness
  • Softer appearance of fine lines and wrinkles
  • Smoother, more even skin tone and texture
  • Safe and effective for all skin types
  • Minimal downtime with natural-looking results

What to expect

Treatment Length: 30 minutes

Downtime: Mild redness or swelling, typically resolves within 24–72 hours

Sessions Required: 3 – 4, spaced 3 weeks apart

Results Last: Up to 6 months, depending on skin condition and lifestyle factors

Prices

Per treatment£325.00 per session
Medical Consultation
Consultation fee is waived if treatment is carried out at the same appointment		£30.00
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Frequently Asked Questions

Yes. Plinest is CE-marked, clinically tested, and has an excellent safety profile. It is suitable for all skin types and particularly beneficial for ageing, sensitive, or compromised skin.

We typically recommend a course of 3 – 4 treatments, spaced approximately 3 weeks apart. After the initial course, maintenance sessions every 4 – 6 months help maintain long-term skin health and results.

You may experience mild redness, swelling, or light bruising at the injection sites. These effects are usually short-lived and resolve within 24–72 hours. Most clients return to normal activities the same or next day.

Some patients notice improvements in skin hydration and radiance within a few weeks. Full benefits such as improved elasticity, texture, and reduction in fine lines typically become more noticeable after the full treatment course is completed.

Yes, as with any injectable treatment, some mild and temporary side effects are possible. These are generally minimal and short-lived.

Common side effects include:

  • Mild redness at the injection site
  • Swelling or slight puffiness
  • Tenderness or a “lumpy” feeling under the skin
  • Light bruising

These effects are typically mild and subside within 24 to 72 hours. Some swelling or lumpiness in the treated area may persist for up to 1 – 2 weeks, especially in more sensitive areas like under the eyes.

We offer a range of targeted solutions using PN-HPT® technology:

  • Plinest® – Ideal for improving skin quality on the face, neck, and décolletage, addressing fine lines, wrinkles, dullness, and acne scars.
  • Plinest® Eye – Specially formulated for the delicate skin around the eyes, reducing dark circles and fine lines.
  • Newest® – A unique combination of PN-HPT® and hyaluronic acid, providing enhanced hydration and skin regeneration.